Abstract
Sweet syndrome is a rare dermatosis characterized by painful erythematous plaques, fever, arthralgia, peripheral leukocytosis, edema in the upper dermis, and intense neutrophil infiltration. The syndrome can be seen together with upper respiratory tract infections, hematological malignancies, drug hypersensitivity, sarcoidosis, autoimmune diseases as well as idiopathic. In patients with ulcerative colitis and psoriasis using azathioprine, emerging skin lesions may be an exacerbation of the underlying autoimmune disease, and rarely may also be azathioprine-induced hypersensitivity syndrome. In such cases, it is important to take Sweet's syndrome into consideration and discontinue the drug in the early period and start appropriate treatment.
References
- Choonhakarn C, Chaowattanapanit S. Azathioprine-induced Sweet’s syndrome and published work. J Dermatol 2013; 40: 267-71.
Abstract
Sweet sendromu ağrılı eritematöz plaklar, ateş, artralji, periferik lökositoz, üst dermiste ödem ve yoğun nötrofil infiltrasyonu ile karakterize nadir görülen bir dermatozdur. Sendrom, üst solunum yolu enfeksiyonları, hematolojik maligniteler, ilaç hipersensitivitesi, sarkoidoz, otoimmün hastalıklar ile birlikte görülebildiği gibi idiyopatik de olabilir. Azatiopurin kullanan ülseratif kolit ve psöriazis hastalarında yeni gelişen cilt lezyonlarının altta yatan otoimmün hastalığın alevlenmesi olabileceği gibi nadiren de azatiopurine bağlı hipersensitivite sendromu da olabilir. Böyle durumlarda Sweet sendromunun göz önünde bulundurulup, erken dönemde ilacın kesilmesi ve uygun tedavinin başlanması önemlidir.
References
- Choonhakarn C, Chaowattanapanit S. Azathioprine-induced Sweet’s syndrome and published work. J Dermatol 2013; 40: 267-71.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Case Report |
| Authors | |
| Publication Date | September 23, 2020 |
| Published in Issue | Year 2020 Volume: 2 Issue: 4 |
Cite
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Assoc Prof Dr Muhammed KIZILGÜL was qualified as an Associated Editor in ACMJ on 15/02/2020,
Assoc. Prof. Dr. Ercan YUVANÇ leaved, Assoc. Prof. Dr. Alpaslan TANOĞLU became the Editör in Chief in ACMJ on 13/05/2020.