Nijmegen breakage syndrome (NBS) is a rare autosomal recessive chromosomal instability typically characterized by microcephaly, growth retardation, bird-like facial appearance, immunodeficiency, radiation hypersensitivity, and a predisposition to malignancies. Patients with NBS have an increased risk for lymphomas, mainly non-Hodgkin's lymphoma (NHL). Diffuse large B-cell lymphoma is one of the most common type of lymphoma in NBS patients. Prognosis is still poor. Herein, we, for the first time, report NBS in fraternal twins and synchronous development of NHL
Nijmegen Breakage Syndrome Non-Hodgkin’s Lymphoma fraternal twins. chromosomal instability
Birincil Dil | İngilizce |
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Konular | Klinik Tıp Bilimleri |
Bölüm | Case Reports |
Yazarlar | |
Yayımlanma Tarihi | 10 Eylül 2023 |
Gönderilme Tarihi | 27 Ocak 2023 |
Yayımlandığı Sayı | Yıl 2023 Cilt: 1 Sayı: 3 |