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Ailesel Akdeniz Ateşi

Yıl 2011, Cilt: 18 Sayı: 4, 139 - 143, 30.12.2011

Öz

Ailesel Akdeniz Ateşi tekrarlayan ateş ve serozit ataklarıyla karakterize otozomal resesif geçişli otoinflamatuar bir hastalıktır. Hastalığa 16. kromozomun kısa kolunda yer alan ve MEFV olarak isimlendirilen genin neden olduğu bilinmektedir. Bugüne kadar 150'den fazla gen mutasyonu tanımlanmış olmasına rağmen hastalığın tanısı halen klinik olarak konulmaktadır. Hastalığın en önemli ve prognozu belirleyen komplikasyonu amiloidozdur. Hem amiloidoz gelişimini engelleyen hem de atak şiddeti ve sıklığını azaltan tek tedavi ajanı kolşisindir. Bu derlemede, bu tarihi hastalıkla ilgili en son bilgileri gözden geçirmeyi amaçladık.

Kaynakça

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Toplam 32 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Derlemeler
Yazarlar

Yunus Ugan

Fatih Ermiş

Yayımlanma Tarihi 30 Aralık 2011
Gönderilme Tarihi 16 Haziran 2011
Yayımlandığı Sayı Yıl 2011 Cilt: 18 Sayı: 4

Kaynak Göster

Vancouver Ugan Y, Ermiş F. Ailesel Akdeniz Ateşi. SDÜ Tıp Fak Derg. 2011;18(4):139-43.

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