Araştırma Makalesi
Yıl 2023,
Cilt: 33 Sayı: 1, 1 - 8, 31.03.2023
Öz
This study aims to characterize and evaluate polyethylene oxide (PEO) and chitosan (CS) nanofibers produced by electrospinning method. Electrospinning solutions were used at three different concentrations (1, 2, 3 wt%) with five different PEO/CS mixing ratios (30/70, 40/60, 50/50, 60/40, 100/0). FESEM, XRD and FTIR tests were applied for characterization of the nanofibers. Antibacterial activity of the nanofibers against Staphylococcus aureus and Klebsiella pneumoniae microorganisms was investigated using disk diffusion method. While 1 wt% of concentration was not suitable to obtain regular nanofibers, the nanofibers were uniform and largely free of beads at the other ones (2, 3 wt%). The average diameters of the nanofibers varied from 59 to 298 nm depending on the concentration and mixing ratio. Strong hydrogen bonds were formed between two polymers, while the crystal structure of PEO did not change significantly when mixed with chitosan. The PEO/CS nanofibers showed no resistance to the selected bacteria.
Anahtar Kelimeler
Chitosan polyethylene oxide electrospinning nanofibers antibacterial activity
Destekleyen Kurum
Çukurova University Scientific Research Projects Unit
Proje Numarası
FDK-2019-11674
Kaynakça
- 1. Cengiz Çallıoğlu F. 2013. Silindirli Elektro Lif Çekim Yöntemi ile Nano Lif Üretimi. Tekstil ve Mühendis, 20(91), 35-49.
- 2. Göktepe F, Mülayim BB. 2015. Elektrik Alan Lif Çekimi (Elektrospinning) ile Nano Liflerden İplik Üretim Yöntemleri. Tekstil ve Mühendis, 22(99), 51-67.
- 3. Antonino RSCMQ, Fook BRDL, Lima EPN, Lima RJS, Fook MVL, Covas CAP, Rached RIF, Lima VAO. 2017. Preparation and Characterization of Chitosan Obtained from Shells of Shrimp. Marine Drugs, 15(141),1-12.
- 4. Ayodele O, Okoronkwo AE, Oluwasina OO, Abe TO. 2018. Utilization of Blue Crab Shells for the Synthesis of Chitosan Nanoparticles and Their Characterization, Songlanakarin J . Sci. Technol, 40(5), 1043-1047.
- 5. Sandeep A, Sangameshwar K, Mukesh G, Chandarktan R, Avinash D. 2013. A Brief Overview on Chitosan Applications. Indo American Journal of PHarmaceutical Research, 3(12), 1564-1574
- 6. Hung L, Nagapudi K, Apkarian R, Chaikof E, 2001. Engineered Collagen–PEO Nanofibers and Fabrics. J. Biomater. Sci. Polymer Edn, 12(9), 979–993.
- 7. Singh Y, Dasgupta S, Nayar S, Bhaskar R. 2020. Optimization of Electrospinning Process & Parameters for Producing Defect-Free Chitosan/Polyethylene Oxide Nanofibers for Bone Tissue Engineering. Journal of Biomaterials Science, Polymer Edition, 31(6), 1-23.
- 8. Stie M, Catke J, Wan F, Chronakis I, Jascobsn J, Nielsen H. 2020. Swelling of Mucoadhesive Electrospun Chitosan/Polyethylene Oxide Nanofibers Facilitates Adhesion to the Sublingual Mucosa. Carbohydrate Polymers, 242, 1-29.
- 9. Amiri N, Ajami S, Shahroodi A, Jannatabadi N, Darbab S, Bazzaz B, Pishavar E, Kalalinia F, Movaffagh J. 2020. Teicoplanin-Loaded Chitosan-PEO Nanofibers for Local Antibiotic Delivery and Wound Healing. International Journal of Biological Macromolecules, 162, 645-656.
- 10. Pan W, Wang J, Sun X, Wang X, Jian J, Zhang Z, Hao Qu C, Zelong Y, Feng G. 2020. Ultra Uniform Metal−Organic Framework-5 Loading Along Electrospun Chitosan/Polyethylene Oxide Membrane Fibers for Efficient PM2.5 Removal. Journal of Cleaner Production, 291, 1-29.
- 11. Kuntzler S, Costa J, Morais M. 2018. Development of Electrospun Nanofibers Containing Chitosan/PEO Blend and Phenolic Compounds with Antibacterial Activity. International Journal of Biological Macromolecules, 117, 800-806.
- 12. Surendhiran D, Li C, Cui H, Lin L. 2020. Fabrication of High Stability Active Nanofibers Encapsulated with Pomegranate Peel Extract using Chitosan/PEO for Meat Preservation. Food Packaging and Shelf Life, 23, 1-9.
- 13. Martinova L, Lubosova D. 2008. Electrospun Chitosan Based Nano Fibers. Research Journal of Textile and Apparel, 12(2), 22-79.
- 14. Lemma SM, Bossard F, Rinaudo M. 2016. Preparation of Pure and Stable Chitosan Nanofibers by Electrospinning in the Presence of Poly Ethylene Oxide. International Journal of Molecular Sciences, 17, 1-16.
- 15. Bizarria MTM, Davila MA, Mei LHI. 2014. Non Woven Nano Fiber Chitosan/Peo Membranes Obtained by Electro Spinning. Brazilian Journal of Chemical Engineering, 31(1), 57-68.
- 16. Min LL, Yuan ZH, Zhong LB, Liu Q, Wu RX, Zheng YM. 2014. Preparation of Chitosan Based Electrospun Nanofiber Membrane and Its Adsorptive Removal of Arsenate from Aqueous Solution. Chemical Engineering Journal, 267, 132-141.
- 17. Rieger KA, Schiffman JD. 2014. Electrospinning an essentialoil: Cinnamaldehyde Enhances the Antimicrobial Efficacy of Chitosan/Poly(Ethylene Oxide) Nanofibers. Carbohydrat Polym, 113, 561-568.
- 18. Noruzi M. 2016. Electrospun Nanofibers in Agriculture and the Food Industry: A review. Society of Chemical Industry, 10, 1-16.
- 19. Koosha M, Mirzadeh H. 2015. Electrospinning, Mechanical Properties, and Cell Behavior Study of Chitosan/PVA Nanofibers, Society For Biomaterials, 103(9), 3081-3093.
- 20. Paipitaka K, Pornprac T, Mongkontalangc P, Techitdheera CW, Pecharapaa W. 2011. Characterization of PVA-Chitosan Nanofibers Prepared by Electrospinning. Science Direct, 8, 101-105.
- 21. Benhabiles MS, Salah R, Lounici H, Drouiche N, Goosen MFA, Mameri N. 2012. Antibacterial Activity of Chitin, Chitosan and Its Oligomers Prepared from Shrimp Shell Waste. Food Hydrocolloids, 29, 48-56.
Yıl 2023,
Cilt: 33 Sayı: 1, 1 - 8, 31.03.2023
Öz
Proje Numarası
FDK-2019-11674
Kaynakça
- 1. Cengiz Çallıoğlu F. 2013. Silindirli Elektro Lif Çekim Yöntemi ile Nano Lif Üretimi. Tekstil ve Mühendis, 20(91), 35-49.
- 2. Göktepe F, Mülayim BB. 2015. Elektrik Alan Lif Çekimi (Elektrospinning) ile Nano Liflerden İplik Üretim Yöntemleri. Tekstil ve Mühendis, 22(99), 51-67.
- 3. Antonino RSCMQ, Fook BRDL, Lima EPN, Lima RJS, Fook MVL, Covas CAP, Rached RIF, Lima VAO. 2017. Preparation and Characterization of Chitosan Obtained from Shells of Shrimp. Marine Drugs, 15(141),1-12.
- 4. Ayodele O, Okoronkwo AE, Oluwasina OO, Abe TO. 2018. Utilization of Blue Crab Shells for the Synthesis of Chitosan Nanoparticles and Their Characterization, Songlanakarin J . Sci. Technol, 40(5), 1043-1047.
- 5. Sandeep A, Sangameshwar K, Mukesh G, Chandarktan R, Avinash D. 2013. A Brief Overview on Chitosan Applications. Indo American Journal of PHarmaceutical Research, 3(12), 1564-1574
- 6. Hung L, Nagapudi K, Apkarian R, Chaikof E, 2001. Engineered Collagen–PEO Nanofibers and Fabrics. J. Biomater. Sci. Polymer Edn, 12(9), 979–993.
- 7. Singh Y, Dasgupta S, Nayar S, Bhaskar R. 2020. Optimization of Electrospinning Process & Parameters for Producing Defect-Free Chitosan/Polyethylene Oxide Nanofibers for Bone Tissue Engineering. Journal of Biomaterials Science, Polymer Edition, 31(6), 1-23.
- 8. Stie M, Catke J, Wan F, Chronakis I, Jascobsn J, Nielsen H. 2020. Swelling of Mucoadhesive Electrospun Chitosan/Polyethylene Oxide Nanofibers Facilitates Adhesion to the Sublingual Mucosa. Carbohydrate Polymers, 242, 1-29.
- 9. Amiri N, Ajami S, Shahroodi A, Jannatabadi N, Darbab S, Bazzaz B, Pishavar E, Kalalinia F, Movaffagh J. 2020. Teicoplanin-Loaded Chitosan-PEO Nanofibers for Local Antibiotic Delivery and Wound Healing. International Journal of Biological Macromolecules, 162, 645-656.
- 10. Pan W, Wang J, Sun X, Wang X, Jian J, Zhang Z, Hao Qu C, Zelong Y, Feng G. 2020. Ultra Uniform Metal−Organic Framework-5 Loading Along Electrospun Chitosan/Polyethylene Oxide Membrane Fibers for Efficient PM2.5 Removal. Journal of Cleaner Production, 291, 1-29.
- 11. Kuntzler S, Costa J, Morais M. 2018. Development of Electrospun Nanofibers Containing Chitosan/PEO Blend and Phenolic Compounds with Antibacterial Activity. International Journal of Biological Macromolecules, 117, 800-806.
- 12. Surendhiran D, Li C, Cui H, Lin L. 2020. Fabrication of High Stability Active Nanofibers Encapsulated with Pomegranate Peel Extract using Chitosan/PEO for Meat Preservation. Food Packaging and Shelf Life, 23, 1-9.
- 13. Martinova L, Lubosova D. 2008. Electrospun Chitosan Based Nano Fibers. Research Journal of Textile and Apparel, 12(2), 22-79.
- 14. Lemma SM, Bossard F, Rinaudo M. 2016. Preparation of Pure and Stable Chitosan Nanofibers by Electrospinning in the Presence of Poly Ethylene Oxide. International Journal of Molecular Sciences, 17, 1-16.
- 15. Bizarria MTM, Davila MA, Mei LHI. 2014. Non Woven Nano Fiber Chitosan/Peo Membranes Obtained by Electro Spinning. Brazilian Journal of Chemical Engineering, 31(1), 57-68.
- 16. Min LL, Yuan ZH, Zhong LB, Liu Q, Wu RX, Zheng YM. 2014. Preparation of Chitosan Based Electrospun Nanofiber Membrane and Its Adsorptive Removal of Arsenate from Aqueous Solution. Chemical Engineering Journal, 267, 132-141.
- 17. Rieger KA, Schiffman JD. 2014. Electrospinning an essentialoil: Cinnamaldehyde Enhances the Antimicrobial Efficacy of Chitosan/Poly(Ethylene Oxide) Nanofibers. Carbohydrat Polym, 113, 561-568.
- 18. Noruzi M. 2016. Electrospun Nanofibers in Agriculture and the Food Industry: A review. Society of Chemical Industry, 10, 1-16.
- 19. Koosha M, Mirzadeh H. 2015. Electrospinning, Mechanical Properties, and Cell Behavior Study of Chitosan/PVA Nanofibers, Society For Biomaterials, 103(9), 3081-3093.
- 20. Paipitaka K, Pornprac T, Mongkontalangc P, Techitdheera CW, Pecharapaa W. 2011. Characterization of PVA-Chitosan Nanofibers Prepared by Electrospinning. Science Direct, 8, 101-105.
- 21. Benhabiles MS, Salah R, Lounici H, Drouiche N, Goosen MFA, Mameri N. 2012. Antibacterial Activity of Chitin, Chitosan and Its Oligomers Prepared from Shrimp Shell Waste. Food Hydrocolloids, 29, 48-56.
Toplam 21 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Giyilebilir Malzemeler |
| Bölüm | Makaleler |
| Yazarlar | |
| Proje Numarası | FDK-2019-11674 |
| Erken Görünüm Tarihi | 28 Mart 2023 |
| Yayımlanma Tarihi | 31 Mart 2023 |
| Gönderilme Tarihi | 30 Kasım 2021 |
| Kabul Tarihi | 26 Mayıs 2022 |
| Yayımlandığı Sayı | Yıl 2023 Cilt: 33 Sayı: 1 |
