VITAMIN C ENRICHMENT APPLICATION TO REDUCE THE RISK OF CARCINOGENIC NITROSAMINE FORMATION IN SMOKED FISH

Aydın Kılıç

doi:10.17780/ksujes.1509215

EN TR

VITAMIN C ENRICHMENT APPLICATION TO REDUCE THE RISK OF CARCINOGENIC NITROSAMINE FORMATION IN SMOKED FISH

Abstract

Vitamin C, with its antioxidant and prooxidant properties, can prevent carcinogenic nitrosamine by chelating residual nitrite. It decreases the formation of nitrosamine. The objective of the study was to determine the protective effect of vitamin C in fish in reducing the formation of biogenic amines and the formation of nitrosamines. In this context, smoked samples were treated with vitamin C and analyzed by preparing in portions with different experiments and stored at ±4°C for different storage conditions. In this regard, putrescine(PUT), cadaverine(CAD), tyramine(TYR), and histamine(HIS) changed during storage. On the other hand, analyzes were also made for nitrosodimethylamine (NDMA), nitrosopiperidine(NPIP), nitrosopyrrolidine(NPYR), nitrosodibutylamine(NDBA). The lowest biogenic amine values are detected in group N2. It was determined that groups had 2.41, 3.66, 0.13, and 1.17(μg/g) biogenic amine values after 30 days, respectively. The obtained results showed that vitamin C had lower histamine and putrescine values than other groups separately. In addition, NDMA, NPYR, and NPYR were detected in nitrite containing groups after 30 days. Finally, Vitamin C containing groups were found to be better in terms of biogenic amines and nitrosamines content. All these results show that vitamin C can be used as a preservative in foods to protect against carcinogens.

Keywords

TÜTSÜLENMİŞ BALIKLARDA KANSEROJEN NİTROSAMİN OLUŞUM RİSKİNİ AZALTMAK İÇİN C VİTAMİNİ ZENGİNLEŞTİRME UYGULAMASI

Öz

Antioksidan ve prooksidan olarak bilinen C vitamini, gıdalarda oluşabilecek kalıntı nitriti şelatlama özelliğine sahiptir. Bu özelliği ile kalıntı nitritten kaynaklanabilecek kanserojen nitrozamin radikallerinin oluşum riskini azaltma özelliğine sahiptir. Bu çalışmanın temel hedefi, füme balıklarda C vitamininin, biyojenik amin ve tüm bunlara bağlı olarak kanserojen nitrozaminlerin oluşumunu azaltmadaki koruyucu etkisini belirlemektir. Bu bağlamda, füme balık örnekleri C vitamini muamele edilmiş ve edilmemiş deney grupları halinde hazırlanarak incelenmiş ve farklı depolama sürelerinde ±4ºC'de depolanmıştır. Bu bağlamda, putresin (PUT), kadaverin (CAD), tiramin (TYR) ve histamin (HIS) değerleri depolama srasında değişmiştir. Öte yandan nitrosamin olarak, örneklerdeki nitrosodimetilamin (NDMA), nitrosopiperidin (NPIP), nitrosopirrolidin (NPYR), nitrosodibutilamin (NDBA) değerleri belirlenmiştir. Deneysel verilere göre en düşük biyojenik amin değerleri N2 grubunda bulunmuştur. Deney gruplarının 30 günlük depolamadan sonra sırasıyla 2.41, 3.66, 0.13 ve 1.17 (µg/g) biyojenik amin değerlerine sahip olduğu belirlenmiştir. Elde edilen sonuçlar, C vitamini eklenen grupların diğer gruplara göre daha düşük histamin ve putresin değerlerine sahip olduğunu göstermiştir. Ayrıca nitrit içeren gruplarda 30 günlük depolamadan sonra NDMA, NPYR, NPYR tespit edilmiştir. Son olarak askorbik asit içeren grupların biyojenik amin ve nitrozamin içeriği açısından daha iyi olduğu tespit edilmiştir. Tüm bu deneysel sonuçlar, C vitamininin gıdalarda kanserojen nitrozamin radikallerinin oluşumunu önlemek amacıyla koruyucu olarak kullanılabileceğini göstermektedir.

Anahtar Kelimeler

Supporting Institution

Hacettepe Üniversitesi, Ömer Halisdemir ve RTE Üniversitesi

Ethical Statement

Not necessary.

Thanks

This study was supported by Hacettepe University, Nigde University, Recep Tayyip Erdogan University and Bagci Fishery Co. in Turkey. The authors would kindly like to thank for every contributions and corporations.

References

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Details

Primary Language

English

Subjects

Food Engineering

Journal Section

Research Article

Authors

Aydın Kılıç ^*
0000-0002-8952-9909
Türkiye

Publication Date

March 3, 2025

Submission Date

July 2, 2024

Acceptance Date

October 3, 2024

Published in Issue

Year 2025 Volume: 28 Number: 1

DOI

https://doi.org/10.17780/ksujes.1509215

IZ

https://izlik.org/JA38WA55JG

Cite

RIS / Bibtex

APA

Kılıç, A. (2025). VITAMIN C ENRICHMENT APPLICATION TO REDUCE THE RISK OF CARCINOGENIC NITROSAMINE FORMATION IN SMOKED FISH. Kahramanmaraş Sütçü İmam Üniversitesi Mühendislik Bilimleri Dergisi, 28(1), 30-37. https://doi.org/10.17780/ksujes.1509215