Diklofenak İlaç Kalıntısının UV ve UV/ H2O2 Yöntemleri ile Gideriminin Karşılaştırılması

Sevde Üstün Odabaşı; Bareera Maryam; Hanife Büyükgüngör

doi:10.17780/ksujes.402625

EN TR

Diklofenak İlaç Kalıntısının UV ve UV/ H2O2 Yöntemleri ile Gideriminin Karşılaştırılması

Öz

Dünya nüfusunun hızlı artışına paralel olarak ilaç tüketimi artış göstermektedir. İlaçlar kullanıldıktan sonra bir kısmı vücut tarafından metabolize edilirken kalan kısmı ise vücuttan idrar yoluyla atılmaktadır. Atıksu arıtma tesislerine ulaşan bu ilaçlar biyolojik yöntemlerle arıtılamamakta ve oradan alıcı ortamlara deşarj edilmektedir. Bu nedenle ilaç kalıntılarının giderimlerinde yüksek verimine sahip olan ileri oksidasyon yöntemleri kullanılmaktadır.

Çalışmada analjezik, antipiretik ve antiromatizmal etkiye sahip olan non-sterodial anti-inflamatuar (NSAİ) ilaç grubuna giren diklofenak ilacından oluşturulan sentetik suyun UV ve UV/H₂O₂ yöntemleri ile giderim verimleri karşılaştırılmıştır. Bu çalışmada ilaç derişimleri LCMS/MS cihazı kullanılarak ölçülmüştür. Çalışma sonucunda diklofenağın UV prosesi ile giderimi %90 verim ile gerçekleşirken UV/H₂O₂ prosesi ile giderim verimi ise %100 bulunmuştur. Bu sonuçlara göre hidrojen peroksit ilavesinin ilaç kalıntılarının gideriminde daha etkili olduğu görülmüştür. Çalışma sonucunda UV ve UV/H₂O₂ prosesleri ile diklofenağın mineralizasyonu ile ilgili kinetik çalışmaları yapılmış ve her iki proses içinde birinci dereceden reaksiyon hız sabitleri belirlenmiştir.

Anahtar Kelimeler

Diklofenak,İlaçlar,LCMS/MS,UV,UV/ H2O2

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Details

Primary Language

Turkish

Subjects

Environmental Engineering

Journal Section

Research Article

Authors

Sevde Üstün Odabaşı ^*
Ondokuz Mayıs Üniversitesi
0000-0003-3533-4089
Türkiye

Bareera Maryam
Ondokuz Mayıs Üniversitesi
0000-0002-5864-1834
Pakistan

Hanife Büyükgüngör
0000-0003-1201-6862
Türkiye

Publication Date

October 23, 2018

Submission Date

March 7, 2018

Acceptance Date

October 5, 2018

Published in Issue

Year 2018 Volume: 21 Number: 3

DOI

https://doi.org/10.17780/ksujes.402625

IZ

https://izlik.org/JA29ZJ44FX

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RIS / Bibtex

APA

Üstün Odabaşı, S., Maryam, B., & Büyükgüngör, H. (2018). Diklofenak İlaç Kalıntısının UV ve UV/ H2O2 Yöntemleri ile Gideriminin Karşılaştırılması. Kahramanmaraş Sütçü İmam Üniversitesi Mühendislik Bilimleri Dergisi, 21(3), 272-279. https://doi.org/10.17780/ksujes.402625

Diklofenak İlaç Kalıntısının UV ve UV/ H2O2 Yöntemleri ile Gideriminin Karşılaştırılması

Comparison of Removal of Diclofenac Pharmaceutical Residue by UV and UV/ H2O2

Abstract

Keywords

Diklofenak İlaç Kalıntısının UV ve UV/ H2O2 Yöntemleri ile Gideriminin Karşılaştırılması

Öz

Anahtar Kelimeler

References

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